Understanding how cells respond to external stimuli is an important goal in biology. The response to external stimuli is the result of interactions between many cellular components. The discovery of RNA-mediated gene regulation system has brought scientists another big surprise regarding the wisdom and power of nature. Quantitative studies of RNA lay at the heart of many gene expression studies. Scientists are correlating both steady state and transient RNA levels at different stages of cellular differentiation and cell death. Many of the biologically relevant RNA being examined exist at very low levels within the complexity of a cell population or clinical sample and thus the purity of the RNAs is the key to acquiring amenable data. As The Normal Human Primary Cell Company, ScienCell Research Laboratories is committed to providing the highest quality of normal human primary cell total RNA and small RNA (siRNA and miRNA). To achieve this goal it is necessary to understand what "high purity total RNA" truly means with respect to various downstream applications. Intactness of mRNA, lack of genomic DNA, the presence of enzymatic inhibitors, and lack of ribosomal RNA in poly(A) preparations are all important aspects of RNA purity. As we continue to gain a better understanding of how these factors affect downstream applications, we will strive to ensure that our normal human primary cell total RNA and micro RNA products exceed the requirements for even the most stringent applications.

total RNA

micro RNA