Astrocyte Conditioned Medium

Astrocytes are the most abundant cells in the central nervous system (CNS). Astrocytes provide a variety of biological functions, such as supporting endothelial cells involved in blood-brain barrier formation, providing nutrients to neurons, maintaining extracellular ion balance, and promoting repair in the CNS. Astrocyte conditioned medium (ACM) has been widely used to support the growth of neurons and endothelial cells in culture. ACM has also been shown to protect neurons from corticosterone-induced damage [1]. ACM is a liquid medium prepared from primary human astrocyte cultures by using astrocyte medium (Catalog #1801) conditioned for 48 hours. The medium is sterile filtered and has a pH of 7.4 when equilibrated in an incubator with an atmosphere of 5% CO2/95% air.

Catalog No.	1811
Country of Manufacture	United States
Product Code	ACM
Size/Quantity	100 ml
Product Use	This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures.
Storage	Store the medium at 4°C. Protect it from light
Shipping Info	Gel ice.
References	[1] Ze-Hua Zhu, Ru Yang, Xin Fu, Yan-Qing Wang and Gen-Cheng Wu (2006) Astrocyte-conditioned medium protecting hippocampal neurons in primary cultures against corticosterone-induced damages via PI3-K/Akt signal pathway. Brain Research 1114(1) 1-10.