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- Human Bladder Microvascular Endothelial Cells
The bladder is a hollow ball, with the wall of the bladder composed of the serosa, muscularis, submucosa, musculris mucosa, and lamina propria. The endothelial cells lining the microvasculature of the circulatory system in the bladder are known to play a critical “gatekeeper” role in the inflammatory process through their ability to recruit circulating immune cells into tissues. Endothelial cells in the bladder wall stimulated with thrombin or tryptase causes phospholipid metabolite production and may contribute to the inflammatory process in interstitial cystitis. HBdMEC provide a useful in vitro model to study the role of endothelial cells in physiological and inflammatory conditions.
HBdMEC from ScienCell Research Laboratories are isolated from human bladder tissue. HBdMEC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10⁵ cells in 1 ml volume. HBdMEC are characterized by immunofluorescence with antibodies specific to VWF/Factor VIII and/or CD31 (PECAM1). HBdMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HBdMEC are guaranteed to further expand for 15 population doublings under the
conditions provided by ScienCell Research Laboratories.
Recommended Medium
It is recommended to use Endothelial Cell Medium (ECM, Cat. #1001) for the culturing of HBdMEC.
| Catalog No. | 4300 |
|---|---|
| Country of Manufacture | United States |
| Product Code | HBdMEC |
| Size/Quantity | 5 x 10⁵ cells/vial. |
| Product Use | HBdMEC are for research use only. They are not approved for human or animal use, or for application in in vitro diagnostic procedures. |
| Storage | Upon receiving, directly and immediately transfer the cells from dry ice to liquid nitrogen and keep the cells in liquid nitrogen until they are needed for experiments. |
| Shipping Info | Dry ice. |
| References | [1] Hossler FE and Monson FC. Microvasculature of the rat urinary bladder. Anat Rec 243: 438?448, 1995. [2]. Alice Rickard, Craig Portell, Pamela J. Kell, Suzanne M. Vinson and Jane McHowat (2005 ) Protease-activated receptor stimulation activates a Ca 2+-independent phospholipase A2 in bladder microvascular endothelial cells. Am J Physiol Renal Physiol 288:F714-F721. |
4300No Publication available at this time
| CAT. NO. | CODE | DESCRIPTION | PRICE | Qty | |
|---|---|---|---|---|---|
| MEDIA | |||||
| 1001 | ECM | Endothelial Cell Medium |
$139.00
As low as:
$92.00
|
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| 8248 | BPF | Bovine Plasma Fibronectin |
$137.00
|
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| MOLECULAR BIOLOGY | |||||
| 4304 | HBdMEC cDNA | Human Bladder Microvascular Endothelial Cell cDNA |
$453.00
|
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| 4305 | HBdMEC tRNA | Human Bladder Microvascular Endothelial Cell Total RNA |
$401.00
|
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| 4306 | HBdMEC Lysate | Human Bladder Microvascular Endothelial Cell Lysate |
$438.00
|
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| 4307 | HBdMEC miRNA | Human Bladder Microvascular Endothelial Cell MicroRNA |
$374.00
|
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| 4309 | HBdMEC gDNA | Human Bladder Microvascular Endothelial Cell genomic DNA |
$438.00
|
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