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- Human Hair Dermal Papilla Cells
The dermal papillae are a highly active group of cells derived from the dermis mesenchyme. Located at the base of the hair follicles, the dermal papillae play a crucial role in hair growth cycle by inducing follicle development from the epidermis to produce hair fiber. Hair growth is tightly regulated by the epithelial-mesenchymal interaction of hair follicular cells, which involves various molecular pathways including BMP and Wnt signaling. A previous study showed that dermal papilla cells gradually lost their hair inductivity and proliferation capacity in long-term cultures. Continuous advancement in culture techniques will help provide better models for studying hair
biology and hair reconstitution in regenerative medicine.
HHDPC from ScienCell Research Laboratories are isolated from human scalp. HHDPC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HHDPC are characterized by their mesenchymal cell morphology and immunofluorescence with antibodies specific to fibronectin and/or CD105. HHDPC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HHDPC are guaranteed to further expand for 5 population
doublings under the conditions provided by ScienCell Research Laboratories.
Recommended Medium
It is recommended to use Mesenchymal Stem Cell Medium (MSCM, Cat. #7501) for culturing HHDPC in vitro.
| Catalog No. | 2400 |
|---|---|
| Country of Manufacture | United States |
| Product Code | HHDPC |
| Size/Quantity | 5 x 10^5 cells/vial |
| Product Use | This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. |
| Storage | Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments. |
| Shipping Info | Dry ice. |
| References | [1] Filsell, W., Little, J.C., Stones, A.J., Granger, S.P. and Bayley, S.A. (1994) Transfection of rat dermal papilla cells with a gene encoding a temperature-sensitive polyomavirus large T antigen generates cell lines retaining a differentiated phenotype. Journal of Cell Science 107:1761-1772. [2] Kim, C.D., Choe, Y., Shim, C., Kim, K. (2002) Interferon Beta secreted from human hair dermal papilla cells inhibits the growth of outer root sheath cells cultured in vitro. Biochem Biophys Res Commun. 290:1133-8. [3] Han, J.H., Kwon, O.S., Chung, J.H., Cho, K.H., Eun, H.C., Kim, K.H. (2004) Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicle. J Dermatol Sci. 34:91-8. |
2400ScienCell Research Laboratories (SRL) takes pride in being a resource for researchers all over the world. The publications listed here are not meant as an endorsement or confirmation of the reliability of the research methods. Our sole intention of sharing the research publications listed here is to provide research related insights and innovations of our products with other researchers.
| CAT. NO. | CODE | DESCRIPTION | PRICE | Qty | |
|---|---|---|---|---|---|
| MEDIA | |||||
| 7501 | MSCM | Mesenchymal Stem Cell Medium |
$139.00
As low as:
$90.00
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| MOLECULAR BIOLOGY | |||||
| 2404 | HHDPC cDNA | Human Hair Dermal Papilla Cell cDNA |
$453.00
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| 2405 | HHDPC tRNA | Human Hair Dermal Papilla Cell Total RNA |
$438.00
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| 2406 | HHDPC Lysate | Human Hair Dermal Papilla Cell Lysate |
$438.00
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| 2407 | HHDP miRNA | Human Hair Dermal Papilla Cell MicroRNA |
$374.00
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| 2409 | HHDPC gDNA | Human Hair Dermal Papilla Cell genomic DNA |
$438.00
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