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Need help with product selection and ordering?
Email us at sales@sciencellonline.com
Need help with scientific inquiries, technical assistance, product applications, and use?
Email us at techsupport@sciencellonline.com
Need help with issues concerning this website?
Email us at webmaster@sciencellonline.com
Have any marketing related inquiries?
Email us at marketing@sciencellonline.com
Need help ordering from abroad?
As the largest cell provider, we are available worldwide.
Please visit our Distributors page to select the company nearest to your location.
We are located at 1610 Faraday Ave, Carlsbad, CA 92008
Call us at (877) 602-8549 or (760) 602-8549
Fax us at (760) 602-8575
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Neurons are dynamically polarized cells responsible for electrochemically transmitting information throughout the nervous system [1]. Neurons are anatomic, functional, and trophic units of the brain [2]. Despite great variability in size and shape, most neurons share common morphological features including a cell body, dendrites, the axon, and the axon terminals. The substantia nigra is a midbrain cluster of mostly dopaminergic neurons involved in behaviors such as learning, addiction, and movement. The substantia nigra has been implicated in disorders such as drug addiction and schizophrenia. Additionally, loss of substantia nigra neurons significantly contributes to the development of Parkinson's disease. Mouse neurons-substantia nigra (MN-sn) are a useful in vitro model for studying a wide variety of disorders including Parkinson's disease, drug addiction, and schizophrenia.
MN-sn from ScienCell Research Laboratories are isolated from embryonic day 14 mouse substantia nigra. MN-sn are cryopreserved as primary cultures and delivered frozen. Each vial contains >1 x 106 cells in 1 ml volume. MN-sn are characterized by immunofluorescence with antibodies specific to neurofilament and β-tubulin III. MN-sn are negative for mycoplasma, bacteria, yeast, and fungi. MN-sn are guaranteed to further culture under the conditions provided by ScienCell Research Laboratories; however, MN-sn are not recommended for expanding or long-term cultures since the cells do not proliferate in culture.
Recommended Medium
It is recommended to use neuronal medium (NM, Cat. #1521) for the culturing of MN-sn in vitro.
Catalog No. | M1550 |
---|---|
Country of Manufacture | United States |
Product Code | MN-sn |
Size/Quantity | 1 x 10^6 cells/vial |
Product Use | This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. |
Storage | Transfer cells directly and immediately from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture is needed for experiments. |
Shipping Info | Dry ice. |
References | [1] Parent, A. (1996) Neurons in Carpenter's Human Neuroanatomy. 9th ed., pp131-198, Williams & Wilkins, Quebec, Canada. [2] Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, M., Watson, J. D. (1989) Molecular biology of the cell. 2nd. ed., New York: Garland. |
No Publication available at this time
CAT. NO. | CODE | DESCRIPTION | PRICE | Qty | |
---|---|---|---|---|---|
MEDIA | |||||
1521 | NM | Neuronal Medium |
$126.00
As low as:
$81.00
|
||
REAGENTS | |||||
0403 | PLL | Poly-L-Lysine, 1 mg/ml |
$16.00
|
||
0303 | DPBS | Dulbecco's Phosphate-Buffered Saline, 500 ml |
$16.00
|
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