Need help ordering from abroad?
As the largest cell provider, we are available worldwide.
Please visit our Distributors page to select the company nearest to your location.
Need help ordering from abroad?
As the largest cell provider, we are available worldwide.
Please visit our Distributors page to select the company nearest to your location.
ScienCell’s ready-to-use 3D human cortical spheroids (SP3D-HCS) are comprised of primary human neurons and astrocytes at a 1:7 coculturing ratio. SP3D-HCS maintain direct cell-cell interactions between neurons and astrocytes and form functional synapses throughout the spheroids. This advanced and ready-to-use cortical spheroid is highly suitable for the study of CNS functions, diseases, and therapeutics.
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ScienCell offers ready-to-use human pulmonary alveolar epithelial cell spheroids (SP3D-HPAEpiS), which express the specific alveolar epithelial type II markers such as SP-A, -B, -C, and –D. These spheroids are ready for experiments at 24 hours post thawing. Learn More
ScienCell’s 3D Human Airway Spheroids (SP3D-HAS) display the markers of basal, ciliated, and goblet cells. These spheroids are great models for studying airway diseases in a simple and high throughput manner.
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ScienCell’s ready-to-use 3D renal proximal tubular epithelial spheroids (SP-HRPTEpiS) display the differentiated epithelial cell marker CK18. Notably, SP3D-HRPTEpiS also have high ACE2 (angiotensin-converting enzyme 2) expression. Our RT-PCR analysis indicate elevated mRNA expression of the renal proximal transport molecule and transporters in 3D spheroids, compared to 2D monolayer. SP3D-HRPTEpiS, therefore, provide a physiological in vitro model to study kidney functions, and immune response of kidney cells to viruses. Learn More
ScienCell’s 3D Mini-Kidney Spheroids (SP3D-HMKS) are generated by co-culturing human primary renal proximal tubular epithelial cells, mesangial cells, and glomerular endothelial cells to enable more accurate prediction of tissue-level outcomes. These human mini-kidneys allow the functional maintenance of cells over time due to a more native, three-dimensional (3D) architecture. In addition, they make it feasible to study kidney diseases that are challenging to model using only epithelial cells such as fibrosis. Learn More
Gain novel biological insights with ScienCell's ready-to-use 3D human calvarial osteoblast spheroids (SP3D-HCOS). In just 24 hours after thawing, researchers can obtain highly functional and homogenous 3D osteoblast spheroids in culture. Learn More
Ready-to-use 3D human chondrocyte-articular spheroid kit (SP3D-HCaS) is an innovative and convenient 3D culture product. In 24 hours after thawing the cryopreserved 3D spheroids, researchers can obtain highly functional and homogenous 3D chondrocyte spheroids. Learn More
To investigate the cellular crosstalk between hepatic stellate cells and sinusoidal endothelial cells during liver diseases such as liver fibrosis and caner metastasis, ScienCell has developed ready-to-use 3D liver co-culture spheroids comprised of hepatic stellate cells and sinusoidal endothelial cells at a 1:4 ratio.
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To more closely mimic the cellular complexity of the liver, ScienCell has developed the ready-to-use 3D liver co-culture spheroids composed of hepatocytes and hepatic stellate cells at a 2:1 ratio. These co-culture spheroids are ideal to study the cellular crosstalk occurred during physiological and pathological liver conditions.
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ScienCell’s 3D human retinal pigment epithelial spheroids display the differentiated epithelial cell marker cytokeratin-18 and deposit apolipoprotein ApoE, a prominent drusen constituent. The 3D RPE spheroid model is an ideal way to model drusen in vitro and study the pathogenesis of related diseases, such as AMD. Learn More
ScienCell’s ready-to-use 3D human trabecular meshwork cell spheroids (SP3D-HTMCS) serve as a valuable in vitro model for studying the functions of TM cells in glaucoma research. Learn More
ScienCell’s ready-to-use 3D mesenchymal stem cell spheroids (SP3D-HMSCS) can be thawed and plated directly in multiwell plates. By RT-qPCR analysis, we demonstrate that SP3D-HMSCS have elevated mRNA expression of pluripotency markers such as Sox2, Nanog, and CD90. Furthermore, chemotaxic factor (CXCR4), anti-inflammatory molecule (PEG2,), as well as other endogenous growth factors (VEGF and FGF2) are highly expressed in 3D MSC spheroids. Learn More
ScienCell’s ready-to-use 3D osteoblast and endothelial cell co-culture spheroids serve as the superior and relevant in vitro models for studying the molecular crosstalk between angiogenesis and osteogenesis during skeletal development and postnatal bone repair. Learn More
ScienCell’s hepatic stellate cells (HSC) spheroids are great models for studying the signaling pathways that govern the hepatic stellate cell activation during liver diseases. Our data reveals that culturing HSC in a physiologically-relevant 3D environment brings these cells back to their native quiescent state. Learn More
ScienCell offers cryopreserved 3D multicellular BBB spheroids comprised of human brain microvascular endothelial cells (HBMEC), brain vascular pericytes, and astrocytes at a 1:1:1 ratio.
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