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The adrenal cortex makes up the perimeter of the adrenal gland and plays an essential role in regulating homeostasis in the body through the secretion of corticosteroid and androgen hormones. The secreted steroids arise from the three zones that form the adrenal gland and these zones provide the framework for the adrenal cortex. The cells in the cortex stem from the mesoderm and form three concentric zones: the zona glomerulosa, zona fasciculate, and zona reticularis. Studies have shown that there is extensive interaction between the cortical and medulla regions of the adrenal gland, with cortical cells located within the adrenal medulla and chromaffin cells located within the adrenal cortex. The close contact of these two cell types implies intercellular exchange and allows for further studies of paracrine signaling between the two adrenal endocrine systems. Adrenal cortical cells can be used for further research of hormonal regulation and steroidogenesis.
HAdCC from ScienCell Research Laboratories are isolated from human adrenal cortical tissue. HAdCC are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HAdCC are characterized by immunofluorescence with antibodies specific to GFAP. HAdCC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HAdCC are guaranteed to further culture for 15 population doublings under the conditions provided by
ScienCell Research Laboratories.
Recommended Medium
It is recommended to use Mesenchymal Stem Cell Medium (MSCM, Cat. #7501) for the culturing of HAdCC in vitro.
| Catalog No. | 3610 |
|---|---|
| Country of Manufacture | United States |
| Product Code | HAdCC |
| Size/Quantity | 5 x 10^5 cells/vial |
| Product Use | This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. |
| Storage | Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keepthe cells in liquid nitrogen until cell culture needed for experiments. |
| Shipping Info | Dry ice. |
| References | [1] Arnold, J., 1866. Ein Beitrag zu der feiner Struktur und dem Chemismus der Nebennieren. Virchows Arch.
Pathol. Anat. Physiol. Klin. Med. 35, 64-107. [2] Bornstein et al. (1994) Intimate contact of chromaffin and cortical cells within the human adrenal gland forms the cellular basis for important intraadrenal interactions. JCEM. 78(1): 225. |
3610ScienCell Research Laboratories (SRL) takes pride in being a resource for researchers all over the world. The publications listed here are not meant as an endorsement or confirmation of the reliability of the research methods. Our sole intention of sharing the research publications listed here is to provide research related insights and innovations of our products with other researchers.
| CAT. NO. | CODE | DESCRIPTION | PRICE | Qty | |
|---|---|---|---|---|---|
| MEDIA | |||||
| 7501 | MSCM | Mesenchymal Stem Cell Medium |
$139.00
As low as:
$90.00
|
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| MOLECULAR BIOLOGY | |||||
| 3614 | HAdCC cDNA | Human Adrenal Cortical Cell cDNA |
$453.00
|
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| 3615 | HAdCC tRNA | Human Adrenal Cortical Cell Total RNA |
$401.00
|
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| 3616 | HAdCC lysate | Human Adrenal Cortical Cell Lysate |
$438.00
|
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| 3617 | HAdCC miRNA | Human Adrenal Cortical Cell MicroRNA |
$374.00
|
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| 3619 | HAdCC gDNA | Human Adrenal Cortical Cell Genomic DNA |
$438.00
|
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