Poly-L-Lysine (PLL) is a synthetic, positively charged amino acid chain that enhances cell adhesion by altering surface charges on the culture substrate [1]. It is commonly used as a coating agent to promote cell adhesion in culture. In addition to promoting cell adhesion, PLL surface treatments improve the survival of many primary cells in culture and support neurite outgrowth. This concentrated solution contains polymers in the 70 - 150 kDa range.
Concentration
1 mg/ml, sterile-filtered.
Product Sheets
0403
Safety Data Sheets
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Certificates of Analysis
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1.) Olsson, M., Hultman, K., Dunoyer-Geindre, S., Curtis, M.A., Faull, R.L.M., Kruithof, E.K.O. & Jern, C. (2016) Epigenetic Regulation of Tissue-Type Plasminogen Activator in Human Brain Tissue and Brain-Derived Cells Gene Regul Syst Bio. 10
2.) Steins, A., Dik, P., MĀller, W.H., Vervoort, S.J., Reimers, K., Kuhbier, J.W., Vogt, P.M., van Apeldoorn, A.A., Coffer, P.J. & Schepers, K. (2015) In Vitro Evaluation of Spider Silk Meshes as a Potential Biomaterial for Bladder Reconstruction PLoS One. 10
3.) Li, J., Zhou, J., Zhang, D., Song, Y., She, J. & Bai, C. (2015) Bone marrow-derived mesenchymal stem cells enhance autophagy via PI3K/AKT signalling to reduce the severity of ischaemia/reperfusion-induced lung injury J Cell Mol Med. 19
4.) Williams M, Villarreal A, Bozhilov K, Lin S, Talbot P. (2013) "Metal and silicate particles including nanoparticles are present in electronic cigarette cartomizer fluid and aerosol." PLoS One. 8: e57987.
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