Rat Astrocyte Conditioned Medium-Serum Free

Astrocytes are the most abundant cells in the central nervous system (CNS). Astrocytes provide a variety of biological functions, such as supporting endothelial cells involved in blood-brain barrier formation, providing nutrients to neurons, maintaining extracellular ion balance, and promoting repair in the CNS. Astrocyte conditioned medium-serum free (ACM-sf) has been widely used to support the growth of neurons and endothelial cells in culture. ACM has also been shown to protect neurons from corticosterone-induced damage [1]. Rat ACM-sf is a liquid medium prepared from primary rat astrocyte cultures by using astrocyte medium (Cat #1801) without serum and conditioned for 48 hours. The medium is sterile filtered and has a pH of 7.4 when equilibrated in an incubator with an atmosphere of 5% CO2/95% air.

Catalog No.	R1811-sf
Country of Manufacture	United States
Product Code	RACM-sf
Size/Quantity	100 ml
Product Use	This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures.
Storage	Store the medium at 4°C. Protect from light.
Shipping Info	Gel ice.
References	[1] Zhu Z, Yang R, Fu X, Wang Y, Wu G. (2006) "Astrocyte-conditioned medium protecting hippocampal neurons in primary cultures against corticosterone-induced damages via PI3-K/Akt signal pathway." Brain Res 1114(1):1-10.