- Home /
- Human Hair Follicular Keratinocytes
Hair follicles are self-renewing structures that cycle and regenerate throughout life and also provide a critical niche for keratinocyte stem cells. The interplay between keratinocytes and the underlying mesenchyme are critical for hair follicle morphogenesis and cycling. Several key developmental pathways are involved in determining follicular keratinocyte fate as well as the differentiation into several distinct cellular layers of the follicle during the growth phase of hair. Studies indicate that follicular keratinocytes are distinct from epidermal keratinocytes in proliferative capacity and CD34 expression.
HHFK from ScienCell Research Laboratories are isolated from the human scalp. HHFK are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. HHFK are characterized by immunofluorescence with antibody specific to cytokeratin-18. HHFK are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HHFK are guaranteed to further expand for 15 population doublings under the conditions provided by ScienCell Research Laboratories.
Recommended Medium
It is recommended to use Keratinocyte Medium (KM, Cat. #2101) for culturing HHFK in vitro.
| Catalog No. | 2440 |
|---|---|
| Country of Manufacture | United States |
| Product Code | HHFK |
| Size/Quantity | 5 x 10^5 cells/vial |
| Product Use | This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures. |
| Storage | Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments. |
| Shipping Info | Dry ice. |
| References | [1] Eckert, R. L., Efimova, T., Dashti, S. R., Balasubramanian, S., Deucher, A., Crish, J. F., Sturniolo, M. and Bone, F. (2002) Keratinocyte survival, differentiation, and death: many roads lead to mitogen-activated protein kinase. J Investig Dermatol Symp Proc 7(1):36-40. [2] Song, P. I., Park, Y. M., Abraham, T., Harten, B., Zivony, A., Neparidze, N., Armstrong, C. A. and Ansel, J. C. (2002) Human keratinocytes express functional CD14 and toll-like receptor 4. J Invest Dermatol 119(2):424-32. [3] de Panfilis, G., Semenza, D., Lavazza, A., Mulder, A. A., Mommaas, A. M. and Pasolini, G. (2002) Keratinocytes constitutively express the CD95 ligand molecule on the plasma membrane: an in situ immunoelectron microscopy study on ultracryosections of normal human skin. Br J Dermatol. 147(1):7-12. |
24401.) Yang YC, Fu HC, Wu CY, Wei KT, Huang KE, Kang HY. (2013) 'Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage.'
2.) Yang YC, Fu HC, Wu CY, Wei KT, Huang KE, Kang HY. (2013) "Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage." PLOS ONE. 8: e79434.
ScienCell Research Laboratories (SRL) takes pride in being a resource for researchers all over the world. The publications listed here are not meant as an endorsement or confirmation of the reliability of the research methods. Our sole intention of sharing the research publications listed here is to provide research related insights and innovations of our products with other researchers.
| CAT. NO. | CODE | DESCRIPTION | PRICE | Qty | |
|---|---|---|---|---|---|
| MEDIA | |||||
| 2101 | KM | Keratinocyte Medium |
$119.00
As low as:
$77.00
|
||
| MOLECULAR BIOLOGY | |||||
| 2445 | HHFK tRNA | Human Hair Follicular Keratinocyte Total RNA |
$401.00
|
||
| 2444 | HHFK cDNA | Human Hair Follicluar Keratinocyte cDNA |
$453.00
|
||
| 2446 | HHFK Lysate | Human Hair Follicular Keratinocyte Lysate |
$438.00
|
||
| 2447 | HHFK miRNA | Human Hair Follicular Keratinocyte MicroRNA |
$374.00
|
||
| 2449 | HHFK gDNA | Human Hair Follicular Keratinocyte genomic DNA |
$438.00
|
||
