Human Hepatocytes

1.) Benjamin Krämer, Ansel P. Nalin, Feiyang Ma, Sarah Eickhoff, Philipp Lutz, Sonia Leonardelli, Felix Goeser, Claudia Finnemann, Gudrun Hack, Jan Raabe, Michael ToVinh, Sarah Ahmad, Christoph Hoffmeister, Kim M. Kaiser, Steffen Manekeller, Vittorio Branchi, Tobias Bald, Michael Hölzel, Robert Hüneburg, Hans Dieter Nischalke, Alexander Semaan, Bettina Langhans, Dominik J. Kaczmarek, Brooke Benner, Matthew R. Lordo, Jesse Kowalski, Adam Gerhardt, Jörg Timm, Marieta Toma, Raphael Mohr, Andreas Türler, Arthur Charpentier, Tobias van Bremen, Georg Feldmann, Arne Sattler, Katja Kotsch, Ali T. Abdallah, Christian P. Strassburg, Ulrich Spengler, William E. Carson, Bethany L. Mundy-Bosse, Matteo Pellegrini, Timothy E. O’Sullivan, Aharon G. Freud, Jacob Nattermann, Single-cell RNA sequencing identifies a population of human liver-type ILC1s, Cell Reports, Volume 42, Issue 1, 2023, 111937, ISSN 2211-1247, https://doi.org/10.1016/j.celrep.2022.111937.

2.) Soronen, J., YkiJrvinen, H., Zhou, Y., Sdevirta, S., Sarin, A., Leivonen, M., Sevastianova, K., Perttil, J., Laurila, P., Sigruener, A., Schmitz, G. & Olkkonen, V.M. (2016) Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease Physiol Rep. 4

3.) Harmon, B., Bird, S.W., Schudel, B.R., Hatch, A.V., Rasley, A. & Negrete, O.A.(2016) 'A GenomeWide RNA Interference Screen Identifies a Role for Wnt/?Catenin Signaling during Rift Valley Fever Virus Infection' J Virol. VOL 90

4.) Yuan, J., Li, W., Huang, J., Guo, X., Li, X., Lu, X., Huang, X. & Zhang, H. (2015) Transplantation of human adipose stem cell-derived hepatocyte-like cells with restricted localization to liver using acellular amniotic membrane Stem Cell Res Ther. 6

5.) Xiao, H., Bid, H.K., Jou, D., Wu, X., Yu, W., Li, C., Houghton, P.J. & Lin, J. (2015) A Novel Small Molecular STAT3 Inhibitor, LY5, Inhibits Cell Viability, Cell Migration, and Angiogenesis in Medulloblastoma Cells* J Biol Chem. 290

6.) Li, J., Zhou, J., Zhang, D., Song, Y., She, J. & Bai, C. (2015) Bone marrow-derived mesenchymal stem cells enhance autophagy via PI3K/AKT signalling to reduce the severity of ischaemia/reperfusion-induced lung injury J Cell Mol Med. 19

7.) Kong, L., Li, S., Huang, M., Xiong, Y., Zhang, Q., Ye, L., Liu, J., Zhu, X., Sun, R. & Guo, Y. (2015) The Roles of Endoplasmic Reticulum Overload Response Induced by HCV and NS4B Protein in Human Hepatocyte Viability and Virus Replication PLoS One. 10

8.) Feng, Y.M., Feng, C.W., Chen, S.Y., Hsieh, H.Y., Chen, Y.H. & Hsu, C.D. (2015) Cyproheptadine, an antihistaminic drug, inhibits proliferation of hepatocellular carcinoma cells by blocking cell cycle progression through the activation of P38 MAP kinase BMC Cancer. 15

9.) Chiang TS, Yang KC, Chiou LL, Huang GT, Lee HS.(2014) "Enhancement of CYP3A4 Activity in Hep G2 Cells by Lentiviral Transfection of Hepatocyte Nuclear Factor-1 Alpha." PloS one. 9: e94885.

10.) Liu Y, Liu A, Xu Z, Yu W, Wang H, Li C, Lin J. (2011) "XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells." Apoptosis. 16: 502-10.

11.) Braconi C, Valeri N, Gasparini P, Huang N, Taccioli C, Nuovo G, Suzuki T, Croce CM, Patel T. (2010) "Hepatitis C virus proteins modulate microRNA expression and chemosensitivity in malignant hepatocytes." Clin Cancer Res. 16: 957-66.

12.) Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N. (2010) "The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib." Hepatology. 52: 1310-21.

13.) Liu Y, Li PK, Li C, Lin J. (2010) "Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells." J Biol Chem. 285: 27429-39.

14.) Shen Q, Cicinnati VR, Zhang X, Iacob S, Weber F, Sotiropoulos GC, Radtke A, Lu M, Paul A, Gerken G, Beckebaum S. (2010) "Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion." Mol Cancer. 9: 227.

15.) Shimizu S, Takehara T, Hikita H, Kodama T, Miyagi T, Hosui A, Tatsumi T, Ishida H, Noda T, Nagano H, Doki Y, Mori M, Hayashi N. (2010) "The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma." J Hepatol. 52: 698-704.

16.) Yeon JH, Na D, Park JK. (2010) "Hepatotoxicity assay using human hepatocytes trapped in microholes of a microfluidic device." Electrophoresis. 31: 3167-74.

17.) Braconi C, Meng F, Swenson E, Khrapenko L, Huang N, Patel T. (2009) "Candidate therapeutic agents for hepatocellular cancer can be identified from phenotype-associated gene expression signatures." Cancer. 115: 3738-48.

18.) Huang Y, Song N, Ding Y, Yuan S, Li X, Cai H, Shi H, Luo Y. (2009) "Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis." Cancer Res. 69: 7529-37.

19.) Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. (2007) "MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer." Gastroenterology. 133: 647-58.

20.) Nahmias Y, Casali M, Barbe L, Berthiaume F, Yarmush ML. (2006) "Liver endothelial cells promote LDL-R expression and the uptake of HCV-like particles in primary rat and human hepatocytes." Hepatology. 43: 257-65.

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