Human bone morphogenetic protein 5 is encoded by the BMP5 gene. It is member of the TGFβ superfamily. Bone morphogenetic proteins are known for their ability to induce bone and cartilage development. BMP5 may play a role in certain cancers. Like other BMP's, BMP5 is inhibited by chordin and noggin. It is expressed in the trabecular meshwork, optic nerve head, lung and liver, and it may have a role in the development and normal function. BMP-5 is mapped on human chromosome 6. The standard used in this kit is recombinant BMP-5 with the monomer molecular mass of 18KDa.
ScienCell's human BMP-5 ELISA Kit is based on standard sandwich enzyme-linked immune-sorbent assay technology. Human BMP-5 specific-specific monoclonal antibodies are precoated onto 8 x 12 divisible strips. The human specific detection monoclonal antibodies are biotinylated. The test samples and biotinylated detection antibodies are subsequently added to the wells and then washed with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex is added and unbound conjugates are washed away with PBS or TBS buffer. HRP substrate TMB is used to visualize HRP enzymatic reaction. TMB is catalyzed by HRP to produce a blue color product that changes into yellow after adding acidic stop solution. The intensity of yellow is proportional to the amount of human BMP-5 that is captured in the strips.
|Country of Manufacture||United States|
|Product Use||This product is for research use only. It is not approved for use in humans, animals, or in vitro diagnostic procedures.|
|Storage||Store at 4°C For Frequent use, at -20°C For infrequent use. Avoid multiple Freeze-thaw cycles.|
|Shipping Info||Shipped on gel ice.|
|References||1. Hahn GV, Cohen RB, Wozney JM, Levitz CL, Shore EM, Zasloff MA, Kaplan FS (Dec 1992). "A bone morphogenetic protein subfamily: chromosomal localization of human genes for BMP5, BMP6, and BMP7". Genomics 14 (3): 759-62.
2. Beck HN, Drahushuk K, Jacoby DB, Higgins D, Lein PJ (Mar 2003). "Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons". BMC Neurosci 2: 12.
3. "Entrez Gene: BMP5 bone morphogenetic protein 5
Are you a regular user of ScienCell products? If so, tell us how you like our products by writing a review and receive a discount for your future purchase.
Has your paper been published using one or more of Sciencell products? Get rewarded! Receive 10% off one order*. See details >>
No Publication available at this time
Certificate of Analysis
Certificate of Analysis for Human BMP-5 ELISA Kit does not exist
For specific lot number search below:
Click on Questions to view answers:
There are no product questions yet.